Diet and Cancer Prevention
Foodtypes

It has been empirically proven that diet is a central environmental factor affecting the process of tumour growth, whether by promoting it or preventing it. Moreover, nutritional factors have a greater influence on some types of cancer than others. This section will prominently look at these elements and their food sources.

  • The human diet has a variety of different types of nutrients - proteins, fat, carbohydrates, vitamins, minerals - and epidemiological studies suggest that the intake of these elements should be assorted. So why has there always been such focus on the foremost value of fruits and vegetables?

    The importance of antioxidants

    • One sort of naturally occurring chemicals found in vegetables, fruits, and grains are phytochemicals, which have cancer-preventive effects. These compounds can prevent carcinogenesis by scavenging DNA reactive agents, suppressing the abnormal proliferation of early damaged cells, and inhibit certain properties of the cancer cell. Phytochemicals are different from vitamins and minerals because they have no nutritional value. Some are antioxidants that help protect against cell lesions. Other examples are:
      • Isochiocyanates: Cruciferous vegetables (cabbage, broccoli, cauliflower, and kale).
      • Flavonoids: Vegetables, citrus fruits, celery, parsley, onions, grains, tea, soybean.
      • Phenolic acids: Tomatoes, citrus fruits, strawberries, raspberries, carrots, whole grains, nuts.
      • Terpenes: Cherries, citrus fruit peel.
      • Polyphenols: Green tea, grapes, wine.

    • Fruits and vegetables also contain substances called antioxidants. These nutrients are in a group of vitamins and minerals and are thought to protect against cancer, heart disease, and maybe normal aging. Antioxidants generally protect cells from oxidative damage, which is a main cause of tumourigenesis. Various antioxidants have different functions; such as deactivate free radicals or transforming them to less toxic substances, as illustrated in the next section.
      • Selenium: Brazil nuts, meat, seafood, eggs, whole grains, legumes.
      • Vitamin A: Greens, squash, carrots, pumpkins, red pepper, sweet potatoes, apricot, cantaloupe, mango, papaya, peaches.
      • Carotenoids (Vit. A related): Dark green leafy vegetables, and yellow, red, orange, vegetables, and fruits.
      • Vitamin C: Citrus fruit, melon, strawberries, pineapple, tomato, pepper, and potatoes.
      • Vitamin E: Wheat germ, vegetable oil, nuts.

    • Also most plant-derived foods are good sources of fibre, which may particularly reduce the risk of colon cancer. Dietary fibre is found in cereal foods, beans, lentils, fruit and vegetables. A diet rich in fibre is associated with reduced risks of many gut diseases, including bowel cancer, since it keeps the large intestines healthy.
  • Nefarious foods

  • As shown above, nutritional ingredients have many anticarcinogens, which can help avoid the potential growth of a tumour. However, foods may also contain carcinogens, although, the respective risk is low because if they are present, it is usually in very small amounts. Nonetheless, carcinogens in foods may be substances that occur naturally, they may be due to contamination, or they may be formed during cooking or processing (e.g. in smoked foods). Aflatoxins, which are toxic metabolites produced by certain fungi in/on foods and feeds, are examples of carcinogens in foods.
  • Despite the fact that there are scarce carcinogens in foods, many types of nutrients have been linked to cancer development. Meat, for instance, if consumed regularly, has a higher effect on tumour growth in the colon. Red meat presents a superior risk than poultry though. Total and saturated fat also affect the same kind of cancer, and animal fat is negatively prevalent over vegetable fat. Another example is alcohol. People who drink large amounts of alcohol have an increased risk of certain types of cancer, particularly liver cancer and cancers in the mouth and oesophagus. Studies have shown that an intake higher than 60g of ethanol per day (roughly a consumption of a standard .75 litre bottle of wine) will increase the risk of one of these cancers 9 times. Moreover, if tobacco consumption is also combined to the drinking habit, the risk will augment to 50 times.
  • Finally, research continues to identify numerous anti-cancer activities of the established essential nutrients as well as phytochemicals. Here follow groups of elements with distinct levels of cancer-fighting activity:
      • Highest level of protection: Cabbage, garlic, ginger, liquorice, soybeans, unbelliferous vegetables (carrots, celery, cilantro, parsley and parsnips).
      • Moderate: Onions flax, citrus, turmeric; cruciferous and solanaceous (tomatoes, peppers) vegetables; brown rice and whole wheat.
      • Lower but still significant: Mints, rosemary, thyme, oregano, sage, basil; oats and barley; cucumber, cantaloupe and berries.